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Ancestor membership does not transfer phenotype values between groups.","importantHtml":""},"sections":[{"bodyHtml":"<p>People with a 15q24 microdeletion are missing between 1.7 million and 6.1 million DNA building blocks (base pairs), also written as 1.7-6.1 megabases (Mb), at position q24 on chromosome 15. The exact size of the deletion varies, but all individuals are missing the same 1.2 Mb region. This region contains several genes that are thought to be important for normal development.</p><p>The signs and symptoms that result from a 15q24 microdeletion are probably related to the loss of one or more genes in the deleted region. However, it is unclear which missing genes contribute to the specific features of the disorder.</p><p class=\"section-source\"><a href=\"https://medlineplus.gov/genetics/condition/15q24-microdeletion/#causes\">MedlinePlus Genetics: Causes</a></p>","key":"forms","title":"What causes 15q24 microdeletion?"},{"bodyHtml":"<p>15q24 microdeletion is associated with mild to moderate intellectual disability and delayed speech development. Other common signs and symptoms include short stature, weak muscle tone (hypotonia), and skeletal abnormalities including loose (lax) joints. Affected males may have genital abnormalities, which can include an unusually small penis (micropenis) and the opening of the urethra on the underside of the penis (hypospadias). Affected individuals also have distinctive facial features such as a high front hairline, broad eyebrows, widely set eyes (hypertelorism), outside corners of the eyes that point downward (downslanting palpebral fissures), a broad nasal bridge, a full lower lip, and a long, smooth space between the upper lip and nose (philtrum).</p><p class=\"section-source\">Source: <a href=\"https://medlineplus.gov/genetics/condition/15q24-microdeletion\">MedlinePlus Genetics</a></p>","key":"overview","title":"Condition overview"}],"sharedSources":[],"slug":"15q24-microdeletion","sourceDocuments":[{"name":"15q24 microdeletion","reviewed":"2011-09","sections":{"causes":{"fetchedAt":"2026-10-20T20:18:47.595937+00:00","label":"Causes","pageSha256":"a5a579b07e20b6d50a89f1e7e8f0448886fdb66d89fa9d49403c247975039c25","sourceUrl":"https://medlineplus.gov/genetics/condition/15q24-microdeletion/#causes","status":"available"}},"source_release":"2026-10-01","url":"https://medlineplus.gov/genetics/condition/15q24-microdeletion"}],"sourceNote":"MedlinePlus descriptions and Causes; original HPO annotations.","takeawayHtml":"Cause explanations are from MedlinePlus Genetics. Feature values below retain their original sources and patient groups.","title":"15q24 microdeletion"},"schemaVersion":1}