Each column keeps its native condition scope. Initial features are displayed alphabetically, not ranked by clinical importance. Counts remain separate, and an empty cell does not mean a feature cannot occur.
"},"coverage":{"countRecords":0,"emptyColumnKeys":[],"hpoRelease":"2026-06-23","narrativeSourceChanges":[],"records":3,"sourceGroups":{"omim":3,"orphanet":0,"published":0}},"features":[{"hpoId":"HP:0000365","label":"Hearing loss","primary":false},{"hpoId":"HP:0000360","label":"Tinnitus","primary":false},{"hpoId":"HP:0002321","label":"Vertigo","primary":false}],"ledeHtml":"Ménière disease is a disorder of the inner ear that affects balance and hearing. This condition is characterized by sudden episodes of extreme dizziness (vertigo), a roaring sound in the ears (tinnitus), a feeling of pressure or fullness in the ears, and fluctuations in hearing. Episodes are often associated with nausea and vomiting, and they can severely disrupt activities of daily living.","mondoId":"MONDO:0007972","records":[{"frequencyKind":"reported","key":"759e8a638221305b33fde5ae79d5ce078437c88a5bcf0988b00d3ff9692abf10","raw":{"aspect":"P","body_system":"ear","disease_id":"OMIM:156000","disease_name":"Meniere disease","evidence":"IEA","frequency_raw":null,"hpo_id":"HP:0002321","is_excluded":false,"label":"Vertigo","onset_id":null,"reference":"OMIM:156000","source_release":"2026-06-23"},"sourceGroups":["omim"]},{"frequencyKind":"reported","key":"8f02de99c10d7ee20f0914d4a56dad21cde8eb69d38a79eef3e42bc5362f3afa","raw":{"aspect":"P","body_system":"ear","disease_id":"OMIM:156000","disease_name":"Meniere disease","evidence":"IEA","frequency_raw":null,"hpo_id":"HP:0000365","is_excluded":false,"label":"Hearing impairment","onset_id":null,"reference":"OMIM:156000","source_release":"2026-06-23"},"sourceGroups":["omim"]},{"frequencyKind":"reported","key":"a9d1a785ac24ece64c1a76ffa73712b95c6f0299c5146950a328b212858c1dd5","raw":{"aspect":"P","body_system":"ear","disease_id":"OMIM:156000","disease_name":"Meniere disease","evidence":"TAS","frequency_raw":null,"hpo_id":"HP:0000360","is_excluded":false,"label":"Tinnitus","onset_id":null,"reference":"OMIM:156000","source_release":"2026-06-23"},"sourceGroups":["omim"]}],"referenceLabels":{},"references":{"causeHtml":"","identityNote":"MONDO cross-references identify native condition entries. Ancestor membership does not transfer phenotype values between groups.","importantHtml":""},"sections":[{"bodyHtml":"The cause of Ménière disease is unknown, although it probably results from a combination of environmental and genetic factors.
Ménière disease is thought to be related to abnormalities of the inner ear, which contains structures that are needed for normal hearing and balance. Episodes of vertigo, tinnitus, and hearing loss likely result from fluctuating amounts of fluid in the inner ear. These changes disrupt signals sent from the inner ear to the brain that are related to sound and the body's position and movement.
Researchers have studied many possible risk factors for Ménière disease, including viral infections, trauma to the inner ear, noise pollution, allergies, abnormal immune system responses, and migraines. Studies have also examined changes in more than a dozen genes that might contribute to the signs and symptoms of this condition. However, none of the factors studied so far appears to play a major role in Ménière disease. Researchers are looking for additional environmental and genetic factors that are associated with this complex disorder.
","key":"forms","title":"What causes Ménière disease?"},{"bodyHtml":"The episodes associated with Ménière disease generally last several hours. Studies suggest that episodes can be triggered by stress, tiredness (fatigue), emotional upset, illness, and dietary factors. The timing of these episodes is unpredictable; affected individuals may experience a cluster of episodes within a short period, followed by months or years without any symptoms.
Ménière disease usually appears in adulthood, most often in a person's 40s or 50s. It is much less common in children and young adults. The symptoms of the disorder typically begin in one ear, although they may later involve both ears.
Some people with Ménière disease have no symptoms of the disorder between episodes, particularly in the early stages of the disease. Over time, however, many affected individuals develop ongoing problems with unsteadiness, tinnitus, and a feeling of fullness in the ears. Additionally, permanent hearing loss eventually develops in many people with this disorder.
Source: MedlinePlus Genetics
","key":"overview","title":"Condition overview"}],"sharedSources":[],"slug":"meniere-disease","sourceDocuments":[{"name":"Ménière disease","reviewed":"2010-06","sections":{"causes":{"fetchedAt":"2026-10-20T20:23:15.848359+00:00","label":"Causes","pageSha256":"2131553123e079b788fd090fdc569b489e52fb73e46c2f5648a48d6ab14d17e9","sourceUrl":"https://medlineplus.gov/genetics/condition/meniere-disease/#causes","status":"available"}},"source_release":"2026-10-01","url":"https://medlineplus.gov/genetics/condition/meniere-disease"}],"sourceNote":"MedlinePlus descriptions and Causes; original HPO annotations.","takeawayHtml":"Cause explanations are from MedlinePlus Genetics. Feature values below retain their original sources and patient groups.","title":"Ménière disease"},"schemaVersion":1}